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Found 40 Liver Disorders trials

A listing of Liver Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Dynamic Nuclear Polarization-MR Spectroscopic Imaging of Hepatocellular Carcinoma Metabolism to Predict Response Following Locoregional or Systemic Therapy
18 years - 99 years
All genders
Phase 2
Interventional
The research study is being conducted to evaluate a new imaging technique for detecting the response of hepatocellular carcinoma (HCC) to locoregional or systemic therapy. Locoregional therapies or LRT are called Transarterial Chemoembolization or TACE, Transarterial Radioembolization or TARE and Microwave Ablation or MWA. Systemic therapies or ST are therapy …
18 years - 100 years
All genders
Phase 1
This is an observational study that will compare the differences in lymphatic flow and anatomy of the central lymphatic system on MRL in the liver cirrhosis patients with and without ascites. In the second part of the study, MRL anatomical and flow changes in the central lymphatic system of patients …
 Infusion System for Hepatic Cancer
18 years - 99 years
All genders
The primary objective is to assess the safety of using the Medtronic Pump with the Codman catheter for hepatic artery infusion (HAI) using a standard chemotherapy drug.
 Research Study on Whether a Combination of 2 Medicines  Works in People With Non-alcoholic Steatohepatitis (NASH)
18 years - 99 years
All genders
This study investigates the effects of a combination of two investigational medications on non-alcoholic steatohepatitis (NASH).The study evaluates whether combining these medications can reduce liver damage associated with NASH.Who can participate: Adults aged 18 and older with histological evidence of NASH can participate.Study details: Participants will take part in a …
 ALTUS: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk
18 years - 99 years
All genders
Observational
For subjects age 18 years and older who are at an increased risk for HCC and for whom HCC surveillance is appropriate, including subjects with cirrhosis or non-cirrhotic subjects with Hepatitis B. Approximately 3,000 subjects are expected to be enrolled, comprised of approximately 2,222 ultrasound surveillance subjects and 778 subjects …
99 years or below
All genders
The main purpose of this study is to see if study drug CAM2029 works and is safe for people with polycystic liver disease (PLD). The study will also look at: • How the study drug affects the body (“pharmacodynamics”) • What the body does to the study drug (“pharmacokinetics”). This is a Phase …
 Mixed Meal Tolerance Test and Cirrhosis Study
1 years - 75 years
All genders
This is a study of 12 subjects with cirrhosis. Blood is collected at CHPS for metabolomic analysis and MMTT. The meal consumed for MMTT will be a convenience-style breakfast. In addition to research testing on blood, urine, and stool, dietary recalls and the Penn Diet Survey will be conducted. The …
18 years - 99 years
All genders
The purpose of the HepQuant SHUNT study is to validate the Disease Severity Index (DSI) from the HepQuant SHUNT Test for likelihood of large esophageal varices by comparing the SHUNT test to the current standard of care, EGD, in patients with chronic liver disease.
99 years or below
All genders
Phase 2
A phase 2B, randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of BMS-986036 in subjects with NASH and compensated cirrhosis. The treatment period is 48 weeks, with drug administered as a once-weekly injection. There is also a follow-up period to assess long-term bone mineral density and immunogenicity. Target population …
18 years - 85 years
All genders
Interventional
The purpose of this study is to see if a test medicine not yet approved for market, named Rifaximin SSD-40IR given Twice Daily, will help to delay the first episode of overt hepatic encephalopathy (OHE) requiring hospitalization, in patients with liver cirrhosis and how safe it is to use in …
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