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Found 16 Colorectal Cancer trials

A listing of Colorectal Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

45 years - 89 years
All genders
Interventional
This is a pragmatic, double-blind, randomized, controlled trial, to evaluate the effect of implementing a CADs system within the routine clinical practice of Canadian healthcare institutions.The main hypothesis of this study is that the ADR in the operating room equipped with the GI genius CADe system will be significantly higher …
99 years or below
All genders
In the last decade, both the incidence and the survival of acute leukemia has been increasing. Therefore, detection of associated illnesses is important. We have recently observed that patients with acute leukemia treated with anthracyclines develop a high rate of symptomatic heart failure. To avoid this life-threatening illness, early detection …
99 years or below
All genders
PURPOSE: The aim of this study is to assess the feasibility of beta-hydroxybutyrate (BHB) supplementation in individuals who are undergoing a standard-of-care colonoscopy or flexible sigmoidoscopy in order to determine whether BHB supplementation is safe and tolerable, whether BHB supplementations increases serum BHB levels, and whether BHB supplementation leads to …
 Collection of Samples from the United States Population for Optimization and Evaluation of Colorectal Cancer (CRC) Plasma Circulating Free-DNA (cfDNA) Marker Panel Performance
45 years - 85 years
All genders
This study is designed to prospectively collect blood samples and clinical data from subjects that have a suspected advanced adenoma or have been newly diagnosed with colorectal cancer and scheduled for resection surgery, and subjects who are at average risk of colorectal cancer and who are scheduled for routine colonoscopy …
 UPCC 31216: Phase I/II Trial of Regorafenib  Hydroxychloroquine  and Entinostat in Metastatic Colorectal Cancer
99 years or below
All genders
Phase 2
The main purpose of this study is to find the best dose of hydroxychloroquine (HCQ) when given in combination with regorafenib and entinostat.
99 years or below
All genders
Phase 2
This is a single-arm phase II study of twenty-one subjects with mucinous adenocarcinoma of the colon, rectum, or appendix with prior systemic therapy with a fluoropyrimidine, oxaliplatin, and irinotecan. Treatment will consist of nivolumab every 4 weeks and ipilimumab every 8 weeks until disease progression, unacceptable toxicity, or 2 years …
 Study Evaluating the Efficacy and Safety of AB928-Based Treatment Combinations in Patients with Metastatic Colorectal Cancer
18 years - 99 years
All genders
Phase 1
This study will evaluate the efficacy of investigational drug treatments combinations in patients with metastatic colorectal cancer.
18 years or above
All genders
Phase 1/2
Interventional
The primary objectives of this study are: (Phase 1b) to investigate the safety and tolerability and to determine the recommended Phase 2 dose (RP2D) for magrolimab in combination with cetuximab; and (Phase 2) to evaluate overall response rate (ORR) of magrolimab in combination with cetuximab in participants with Kirsten rat …
 Study to Evaluate Imaging Feasibility,  Safety and Diagnostic Performance Post Dosing of an Intraoperative Fluorescent Imaging Agent for Detection of Metastatic Lymph Nodes  Primary Tumors and Tumor Margins in Patients with Solid Tumors
18 years - 99 years
All genders
Phase 2
The purpose of this research study is to learn about the safety and effectiveness of using ONM 100 to obtain images of primary tumors and metastatic lymph nodes in patients with solid tumors undergoing routine surgery. Adults at least 18 years of age with a Biopsy-confirmed diagnosis of primary or …
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