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Found 49 Solid Tumors trials

A listing of Solid Tumors medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

12 years - 99 years
All genders
Phase 2
Interventional
This is a study to evaluate the efficacy and safety of Belzutifan monotherapy in participants with advanced pheochromocytoma/paraganglioma (PPGL) or pancreatic neuroendocrine tumor (pNET). The primary objective of the study is to evaluate the objective response rate (ORR) of belzutifan per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST …
 A Phase 1 Study of the Highly-selective RET
99 years or below
All genders
Phase 1
This is a phase 1 study with Highly-selective RET inhibiter, Blu-667, in patients with Thyroid Cancer, Non-Small cell lung cancer and other advanced solid tumors. The study will be conducted at multiple centers in the United States and Europe. the purpose of this trial is to determine the maximum tolerated …
 Study to Evaluate Imaging Feasibility,  Safety and Diagnostic Performance Post Dosing of an Intraoperative Fluorescent Imaging Agent for Detection of Metastatic Lymph Nodes  Primary Tumors and Tumor Margins in Patients with Solid Tumors
18 years - 99 years
All genders
Phase 2
The purpose of this research study is to learn about the safety and effectiveness of using ONM 100 to obtain images of primary tumors and metastatic lymph nodes in patients with solid tumors undergoing routine surgery. Adults at least 18 years of age with a Biopsy-confirmed diagnosis of primary or …
 A071701 Genomically-Guided Treatment Trial in Brain Metastases
18 years - 99 years
All genders
Interventional
This phase II trial studies how well genetic testing works in guiding treatment for patients with solid tumors that have spread to the brain. Several genes have been found to be altered or mutated in brain metastases such as NTRK, ROS1, CDK or PI3K. Medications that target these genes such …
 A Study of CDK-002 (exoSTING) in Subjects with Advanced/Metastatic  Recurrent  Injectable Solid Tumors  with Emphasis on Squamous Cell Carcinoma of the Head and Neck  Triple Negative Breast Cancer  Anaplastic Thyroid Carcinoma  and Cutaneous Squamous Cell Carcinoma
18 years - 99 years
All genders
Phase 1
Interventional
Consider this study if you have cancer that is considered advanced and/or has spread to other parts of your body. You have received treatment for your cancer but your cancer has come back or has worsened following that treatment. As part of this study, you will complete routine procedures that …
99 years or below
All genders
Phase 3
This purpose of this study is to see if an investigational inhaled medication is safe and effective for the treatment of parainfluenza virus(PIV) in patients with weakened immune systems. Key eligibility criteria are being diagnosed with PIV having received a solid organ or stem cell transplant at any time in …
 Observation of Residual Cancer With Liquid Biopsy Evaluation (ORACLE)
18 years - 99 years
All genders
Observational
The purpose of ORACLE is to demonstrate the ability of a novel ctDNA assay developed by Guardant Health to detect recurrence in individuals treated for early-stage solid tumors. It is necessary that ctDNA test results are linked to clinical outcomes in order to demonstrate clinical validity for recurrence detection and …
 A Study Using the CIVO Platform to Evaluate Intratumoral Microdoses of Anti-Cancer Therapies in Patients with Solid Tumors
18 years - 99 years
All genders
Phase 1
Observational
A study designed to study the localized pharmacodynamics (PD) of anti-cancer therapies within the tumor microenvironment (TME) when administered intratumorally in microdose quantities via the CIVO device in patients with surface accessible solid tumors for which there is a scheduled surgical intervention.
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