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Found 70 Chemotherapy trials

A listing of Chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

18 years - 99 years
All genders
Phase 2
This study is being done to evaluate if participants with HER2-positive breast cancer who have no cancer remaining at surgery after 12 weeks of chemotherapy and two HER-targeting therapies eliminate further chemotherapy after surgery. Eligible subjects would be those with HER2-positive breast cancer.
 Testing the Combination of Pevonedistat With Chemotherapy for Bile Duct Cancer of the Liver
18 years - 99 years
All genders
Phase 2
Interventional
This trial studies how well pevonedistat alone or in combination with chemotherapy (paclitaxel and carboplatin) works in treating patients with bile duct cancer of the liver. Pevonedistat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as …
 Study of Immune Checkpoint Inhibition with Chemotherapy in Treatment-Na ve Metastatic Anal Cancer Patients
18 years - 99 years
All genders
Interventional
This trial compares the addition of nivolumab to chemotherapy (carboplatin and paclitaxel) versus usual treatment (chemotherapy alone) for the treatment of anal cancer that has spread to other places in the body (metastatic). Chemotherapy drugs, such as carboplatin and paclitaxel, work in different ways to stop the growth of tumor …
 Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia
18 years - 39 years
All genders
Phase 3
Interventional
The first purpose of this study is to test the safety of the addition of a drug called inotuzumab to the usual chemotherapy drugs used for adolescent young adults (ages 18-39). Inotuzumab is investigational and is not FDA-approved. Additionally,this study is to compare any good and bad effects of using …
18 years - 99 years
All genders
Phase 2
This research study is being conducted to assess the safety and efficacy of IPH4102, an investigative medication (medication not approved by the Food and Drug Administration (FDA) for subjects diagnosed with Sézary Syndrome (SS) or Mycosis Fungoides (MF) over the age of 18. Participants will be asked to complete the …
99 years or below
All genders
The main purpose of this research study is to find out whether Selective Internal Radiation Therapy (SIRT) preceding a standard chemotherapy treatment can improve survival in patients with cholangiocarcinoma in the liver, compared to chemotherapy alone.
 REVOLUTION: Trial to Evaluate Immunotherapy Combinations with Chemotherapy for the Treatment of Patients with Previously Untreated Metastatic Pancreatic Adenocarcinoma
18 years - 99 years
All genders
Phase 1
This is a phase 1 study that enrolls subjects with metastatic pancreatic adenocarcinoma. The purpose of this study is to learn about the safety and efficacy of a combination of 4 study drugs: ipilimumab (ipi), nab-paclitaxel (nP), gemcitabine (gem), and hydroxychloroquine (HCQ). This is an open-label, non-randomized, exploratory platform trial …
18 years - 99 years
All genders
Interventional
The purpose of this research study is to compare the performance of the investigational (experimental) tricuspid valve repair system plus optimal drug therapy with optimal drug therapy alone. Participants will be randomly assigned to treatment with either the TriClip device (device group) or No TriClip device (control group). Participants will …
 Open Label Study Investigating the Efficacy and Safety of Roxadustat for Treatment of Anemia in Patients Receiving Chemotherapy Treatment for Non-Myeloid Malignancies
18 years - 99 years
All genders
Phase 2
The main purpose of this study is to find out if the experimental drug roxadustat (also known as FG-4592) is safe and effective for potentially treating anemia in people receiving chemotherapy treatments for cancer. 800x600 Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 In order to take part in …