A listing of HIV medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The primary objective of this study is to evaluate the safety and tolerability of a combination of the broadly neutralizing antibodies (bNAbs) GS-5423 and GS-2872 in combination with the HIV capsid inhibitor lenacapavir (LEN).
The purpose of this study is to explore possible neurological complications resulting from prior COVID-19 infection. Neurological symptoms, including ‘brain fog’, depression, and/or anxiety can be disabling. This study aims to determine the prevalence and severity of these symptoms. Unfortunately, little is known about these neuropsychiatric symptoms, particularly in patients …
The purpose of this research study is twofold: to study the role HIV has on the brain’s function and more particularly, the relationship between HIV and stroke; and to study how the presence of HIV effects robot-assisted rehabilitation after stroke, and its association with clinical improvement.
The objective of this proposal is to examine the utility of a robot-based approach to study instrumental activities of daily living (IADLs) function and cognitive-motor performance in persons aging with HIV. IADLs often require high levels of executive functioning during the performance of motor activities, but there are no good …
The purpose of this study is to investigate different oral and systemic problems including dental carries, periodontal disease, dry mouth, high cholesterol, diabetes, heart disease, and osteoporosis, observed in patients living with HIV on antiretroviral therapy.
The primary objective of the PURPOSE2 study is to evaluate the efficacy of lenacapavir (LEN) in preventing the risk of contracting human immunodeficiency virus (HIV). The study will be conducted in 2 parts: a cross-sectional study (Incidence Phase) and a double-blind, randomized study (Randomized Phase).1) The Incidence Phase will include …
The purpose of this study is to determine if you may be eligible to participate in one of ourcurrent research studies being conducted at the University of Pennsylvania. The purposes ofthese studies are to test different methods that might protect people against viruses thatcause transmittable infections or to develop better …
This study is meant for patients who have difficulty taking their HIV meds as prescribed. One goal of the study is to test the effectiveness of long-acting antiretroviral therapy (ART) -- a once-a-month injection that replaces daily ART pills. You will also receive compensation for participating in this study, with …
Both HIV infection and exposure to opioids, including intravenous heroin in people who inject drugs (PWIDs), are associated with systemic immune activation due to, at least partially, dysbiosis and increased microbial translocation from the gut. Medication-assisted treatment (MAT) approaches based on the administration of Opioid Receptor (MOR) agonists (e.g. methadone) …