Found 387 Neoplasms trials
A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Open Label Study Investigating the Efficacy and Safety of Roxadustat for Treatment of Anemia in Patients Receiving Chemotherapy Treatment for Non-Myeloid Malignancies
The main purpose of this study is to find out if the experimental drug roxadustat (also known as FG-4592) is safe and effective for potentially treating anemia in people receiving chemotherapy treatments for cancer. 800x600 Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 In order to take part in …
A Phase I/II Open Label Multi-center Non-randomized Dose Escalation and Dose Expansion Study of AMXI-5001 in Patients with Advanced Malignancies
The purpose of this study is to help define the proper dose amounts, safety and benefits of AMXI-5001 in participants 18 years and older, who have the disease which the study drug may treat, for example, cancer. This study is the first time AMXI-5001 has been given to people. We …
UPCC 45421 Phase I/II study to reduce post-transplantation cyclophosphamide dosing for older or unfit patients undergoing bone marrow transplantation for hematologic malignancies
Certain blood cancers are treat blood or bone marrow transplants. Sometimes the donor cells attack the recipient's body, called GVHD. Cyclophosphamide helps reduce the risk and severity of GVHD .Researchers want to learn if using a lower dose of cyclophosphamide may reduce the drug's side effects while maintaining its effectiveness.
MIRASOL: A Randomized Open-label Phase 3 Study of Mirvetuximab Soravtansine vs. Investigators Choice of Chemotherapy in Advanced High- Grade Epithelial Ovarian Primary Peritoneal or Fallopian Tube Cancers with High Folate Receptor-Alpha Expression
The primary objective is to compare the PFS of patients randomized to MIRV vs. IC Chemo. Secondary objectives include: To compare the ORR of patients randomized to MIRV vs. IC Chemo, to compare OS of patients randomized to MIRV vs. IC Chemo, and to compare the primary patient-reported outcome (PRO) …
A Phase 1 Study of the Highly-selective RET
This is a phase 1 study with Highly-selective RET inhibiter, Blu-667, in patients with Thyroid Cancer, Non-Small cell lung cancer and other advanced solid tumors. The study will be conducted at multiple centers in the United States and Europe. the purpose of this trial is to determine the maximum tolerated …
PILOT STUDY EVALUATING THE UPTAKE OF [18F]F-GLN BY PET/CT IN BREAST CANCER
This is a pilot study in patients with known or suspected primary or metastatic breast cancer with one lesion that is 1.5 cm in diameter or greater may be eligible for this study. Patients may participate in this study if they are at least 18 years of age. Up to …
Imaging of Central Nervous System Tumors Using Indocyanine Green (TumorGlow - CNS)
The research study is being conducted to determine if a same-day intravenous (into a vein) injection of indocyanine green (ICG) detected using an imaging system, can be a useful tool in identifying and differentiating tumor tissue from normal tissues.
UPCC 03121: AURORA US: Prospective Biospecimen Repository in Metastatic Breast Cancer
The purpose of this research is to increase the understanding of tumor spread and treatment benefit in the setting of metastatic breast cancer. Study participation involves the collection of tissue and blood specimens for use in breast cancer research.
A Study of CDK-002 (exoSTING) in Subjects with Advanced/Metastatic Recurrent Injectable Solid Tumors with Emphasis on Squamous Cell Carcinoma of the Head and Neck Triple Negative Breast Cancer Anaplastic Thyroid Carcinoma and Cutaneous Squamous Cell Carcinoma
Consider this study if you have cancer that is considered advanced and/or has spread to other parts of your body. You have received treatment for your cancer but your cancer has come back or has worsened following that treatment. As part of this study, you will complete routine procedures that …
Genomic Epigenetic Proteomic Metabolomic and Immunologic Characterization of Metastatic Neuroendocrine Tumors Surviving Transarterial Embolotherapy
mNET is commonly treated with TACE or TACE. mNET cells can survive TACE or TARE ischemic conditions. In this study, we will biopsy mNETs being treated with TACE or TARE prior to treatment, after treatment, and again at recurrence to characterize the metabolic, immunologic, and genetic profile of the cells …
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