Found 30 Dementia trials
A listing of Dementia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The purpose of this clinical study is to learn about the safety of CT1812 and how well your body tolerates a once-a-day dose of CT1812. The study will also test how well CT1812 will treat mild to moderate dementia with Lewy Bodies.
The longstanding view has been that insomnia, and other forms of sleep disturbance, emerge as a consequence of dementia and are the result of progressive neuronal damage. However, there is growing evidence that the direction of causation may go both ways, with sleep disturbance potentially increasing vulnerability to dementia. Longitudinal …
The purpose of this study is to identify the relationship between chronic sleep disturbance and proteins in spinal fluid that are related to dementia and a molecule called orexin that helps regulate wakefulness and appetite in the brain. Individuals with sleep problems and good sleepers will be asked to participate.
To collect Tau PET imaging in cognitively normal older African American (AA) adults in the ABCD2 study to determine relationship to clinical, cognitive, and other biomarker data. Findings from this study will likely provide insight into the mechanisms and distinctions of age-related cognitive decline and that of Alzheimer's disease. Eligible …
The purpose of this study (ALLFTD) is to understand how Frontotemporal Lobar Degeneration (FTLD) syndromes progress over time, and to develop new tools to help with diagnosis and eventual treatment. The study is enrolling patients with FTLD syndromes. Additionally, the study is enrolling healthy members of families where there is …
This open-label, single arm clinical study is being conducted to assess the long-term safety and efficacy of aducanumab in participants with Alzheimer's disease who were actively participating in Aducanumab clinical studies 103, 205, 301, or 302 (aducanumab feeder studies) as of March 21st 2019. Participants who participated in 221AD302 will …
The overall purpose of this research is to understand the risk factors for Alzheimers disease after Traumatic Brain Injury, including time since diagnosis, ethnicity, and genetic predictors. It is the goal of this multi-center project to disentangle the multiple factors determining individualized brain response to injury and late-life outcomes in …
Evaluate the safety, tolerability, and immunogenicity of 3 dose levels of PR006A administered via sub-occipital injection into the cisterna magna and Quantify PGRN levels in blood and CSF. Please refer to section 2 of the attached protocol. Please refer to section 2 of the attached protocol.
The research study is being conducted to test the safety and tolerability (i.e., possible side effects) of an investigational drug called AL001 and to find out what effects AL001 has on the body. This is for people who have a confirmed progranulin gene mutation that causes frontotemporal dementia (FTD). Study …
The research study is being conducted to learn whether an investigational drug called lebrikizumab could impact how effective certain vaccines may be and how effective and safe the study drug is in patients with moderate-to-severe AD compared with placebo. Research procedures include: Physical exam, Medical History, blood and urine tests, …
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