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Found 8 Spinal Cord Disorders trials

A listing of Spinal Cord Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

18 years - 100 years
All genders
The purpose of this study is to evaluate memory, language and cognitive difficulties in patients with ALS. ALS is a neurological disease that affects nerve cells (motor neurons) in the brain and spinal cord. This condition largely affects the muscles however there are some individuals who also experience other neurological …
18 years - 50 years
All genders
Phase 2
The main purpose of this study is to learn if a vaccine that is given as two shots (injections) to prevent spinal meningitis (an infection of the lining of the brain and spinal cord caused by Neisseria meningitidis type B) might also work in preventing gonorrhea (caused by Neisseria gonorrhoeae). …
 MT-3921- Phase 2  Study to Assess the Efficacy and Safety of MT-3921 in Subjects with Acute Traumatic Cervical Spinal Cord Injury
18 years - 70 years
All genders
Phase 2
MT-3921 is an investigational monoclonal antibody therapy for patients with severe (AIS grade A-C) traumatic cervical spinal cord injury (SCIs). This study aims to compare the efficacy of MT-3921 to a placebo with regard to improving patients sensory and motor function and overall quality of life. Additionally this study aims …
99 years or below
All genders
Phase 2
The objectives of the study are to assess the safety and efficacy of elezanumab in subjects with acute traumatic cervical SCI. The primary endpoint is the Upper Extremity Motor Score (UEMS), a subscore of the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI, 2019 criteria) during the treatment …
 BEAT-MS Multiple Sclerosis Trial
18 years - 55 years
All genders
This is a multi-center prospective rater-masked (blinded) randomized controlled trial of 156 participants, comparing the treatment strategy of Autologous Hematopoietic Stem Cell Transplantation (AHSCT) to the treatment strategy of Best Available Therapy (BAT) for treatment-resistant relapsing multiple sclerosis (MS). Participants will be randomized at a 1 to 1 (1:1) ratio.All participants will be followed …
18 years - 70 years
All genders
Phase 1
Interventional
The purpose of this research study is to learn more about a study drug that may affect patients with spinocerebellar ataxia type 3 (SCA3). This type of drug is called an antisense oligonucleotide. Eligible participants in this study will have the study drug injected into the fluid surrounding their spinal …
 Analyses of Complement and Other Candidate Fluid Biomarkers in Schizophrenia Spectrum Disorders
18 years - 50 years
Accepts healthy volunteer
All genders
The purpose of this research study is to identify biological markers for schizophrenia and related mental illnesses. We are gathering medical information, behavioral assessments, cells and genetic material (DNA), as well as blood and cerebrospinal fluid (CSF), and brain images from persons who appear to have a psychiatric disorder and …
 Chronic insomnia and CSF markers of dementia
30 years - 59 years
All genders
The purpose of this study is to identify the relationship between chronic sleep disturbance and proteins in spinal fluid that are related to dementia and a molecule called orexin that helps regulate wakefulness and appetite in the brain. Individuals with sleep problems and good sleepers will be asked to participate.