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Found 26 Multiple Myeloma trials

A listing of Multiple Myeloma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Maintenance Therapy in Patients with Multiple Myeloma (MM) Using Minimal Residual Disease (DRAMMATIC Study)

Maintenance Therapy in Patients with Multiple Myeloma (MM) Using Minimal Residual Disease (DRAMMATIC Study)

17 years - 75 years
All genders
Interventional
This study will examine whether adding the drug daratumumab/rHuPH20 to the usual maintenance treatment with lenalidomide after stem cell transplant help multiple myeloma patients survive longer. For patients who do not have minimum residual disease [MRD-negative], this study is also trying to determine if maintenance therapy should be stopped after …
 A Study to Evaluate the Safety of bb2121 in Subjects With High Risk, Newly Diagnosed Multiple Myeloma (NDMM) (KarMMa-4)

A Study to Evaluate the Safety of bb2121 in Subjects With High Risk, Newly Diagnosed Multiple Myeloma (NDMM) (KarMMa-4)

18 years - 99 years
All genders
This is a multicenter, open-label, phase 1, single arm study intended to determine the optimal target dose and safety of bb2121 in subjects with HR (R-ISS Stage III per IMWG criteria) NDMM. Subjects should have received 3 Cycles of standard induction therapy prior to undergoing leukapheresis procedure to collect autologous …
 Expanded Access Protocol (Eap) For Subjects Receiving Idecabtagene Vicleucel That Is Nonconforming

Expanded Access Protocol (Eap) For Subjects Receiving Idecabtagene Vicleucel That Is Nonconforming

18 years - 99 years
All genders
Observational
This study is designed to provide patients access to their nonconforming ide-cel as a treatment option for their disease. The study will evaluate the safety and effectiveness of this therapy through the collection of information. You may or may not receive direct medical benefit from participating in this study. The …
 Multicenter Interventional Lymphangioleiomyomatosis Early Disease Trial (MILED Trial)

Multicenter Interventional Lymphangioleiomyomatosis Early Disease Trial (MILED Trial)

All genders
This application is a request to execute a reliance agreement with the Cincinnati Children's Hospital Medical Center (CCHMC) IRB.
 Tissue Collection for Multiple Myeloma Research

Tissue Collection for Multiple Myeloma Research

18 years - 99 years
All genders
Interventional
The primary purpose of this research study is to obtain specimens (blood, bone marrow, and other tissues) for research about multiple myeloma and related diseases.

UPCC 43419: Prospective Study of Immune Biomarkers in Patients with Multiple Myeloma

All genders
The objective of this exploratory observational cohort study is to obtain blood samples - and in some cases, bone marrow aspirate samples - from patients with multiple myeloma for study in the laboratory.

UPCC 08423: PHASE 2 SINGLE-ARM NON-INFERIORITY STUDY OF LIMITED-DURATION TECLISTAMAB FOR RELAPSED REFRACTORY MULTIPLE MYELOMA

All genders
Phase 2
Please refer to Protocol Section 4 Please refer to Protocol Section 4 Please refer to Protocol Section 4

UPCC 19418: A Phase 1/2a Dose-Finding Study of PT-112 in Patients with Relapsed or Refractory Multiple Myeloma

All genders
Phase 1
Multicenter, open-label study of PT-112 in patients with relapsed/refractory MM. The study will be conducted in two parts. The first part of the study involves dose-escalation, in which successive cohorts of patients will receive escalating doses of PT-112 until the maximum tolerated dose (MTD) is reached. The second part of …
 DREAMM 2

DREAMM 2

18 years - 99 years
All genders
Phase 2
This research study is being done to learn more about multiple myeloma and if the study drug, GSK2857916, can improve multiple myeloma in patients who have already failed other treatments.
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