Found 30 Wounds trials
A listing of Wounds medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The purpose of this study is to better understand the mechanism of action of cladribine tablets. The study will generate hypotheses regarding the impact of cladribine tablet activity in the CNS by assessing the cerebrospinal fluid (CSF) levels of lymphocyte subsets, neuronal injury markers, & soluble immunological markers in study …
Opioids activate the limbic system and results in acute cell injury hippocampal atrophy. Thespecific aims of this proposal are to test the hypotheses that humans with chronic pain on longterm,high-dose opioids: 1. Will demonstrate smaller hippocampal volumes by MRI. 2. Willperform more poorly on neuropsychological tests of memory and associated …
MT-3921 is an investigational monoclonal antibody therapy for patients with severe (AIS grade A-C) traumatic cervical spinal cord injury (SCIs). This study aims to compare the efficacy of MT-3921 to a placebo with regard to improving patients sensory and motor function and overall quality of life. Additionally this study aims …
The LATMI study uses functional MRI scans to characterize the response of neural blood vessels to increased CO2 levels. TBI patients will undergo assessments and follow up to determine the healing capacity of cerebral vasculature after TBI. Additionally, the study aims to understand the role of endothelial progenitor cells in …
Traumatic cerebrovascular injury (TCVI) is common after traumatic brain injury (TBI) and an attractive target for therapeutic intervention. We will longitudinally measure cerebrovascular reactivity (CVR) by functional near-infrared spectroscopy (fNIRS) in acute (3 days from injury), subacute, and chronic phases after TBI as a biomarker of TCVI as compared to …
The objectives of the study are to assess the safety and efficacy of elezanumab in subjects with acute traumatic cervical SCI. The primary endpoint is the Upper Extremity Motor Score (UEMS), a subscore of the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI, 2019 criteria) during the treatment …
A Single-blind, Phase 2, Multi-center, Randomized Study to Assess Safety, Tolerability, Efficacy and Pharmacokinetics of the Relaxin Agonist R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients with Hepatorenal Syndrome-Acute Kidney Injury
The primary objective of the study is to assess the effect of preventing preservation-related graft injury with the use of the metra® device in enrolled subjects. The single-arm continued access phase will be used to collect additional effectiveness and safety data to support the objectives and outcomes of the original …
Adults 65 and older are more likely to have significant injuries from minor things like falls. They can have problems regaining strength due to sarcopenia (loss of muscle tissue as part of natural aging process). Nicotinamide riboside/pterstilbene (Basis) is commercially available nutraceutical. This randomized, double blind placebo controlled trial will …
Have you experienced a traumatic event that affected your life significantly? You may be eligible to participate in a study conducted by the Center for the Treatment and Study of Anxiety at the University of Pennsylvania.In this study we will investigate the influence of gonadal hormones on fear acquisition and extinction …
