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Found 41 Aging trials

A listing of Aging medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Aging Brain Cohort Dedicated to Diversity Study TAU PET

All genders
Phase 2
To collect Tau PET imaging in cognitively normal older African American (AA) adults in the ABCD2 study to determine relationship to clinical, cognitive, and other biomarker data. Findings from this study will likely provide insight into the mechanisms and distinctions of age-related cognitive decline and that of Alzheimer's disease. Eligible …

UPCC 42422: A Phase 1/2 Multicenter Open-Label Randomized Dose Ranging and Expansion Study of the Combination of Gilteritinib Venetoclax and Azacitidine in Patients with Newly Diagnosed FLT3 Mutated Acute Myeloid Leukemia (AML) not Eligible for Intensive Induction Chemotherapy

All genders
Gilteritinib, given with venetoclax and azacitidine, is a potential new treatment for people with acute myeloid leukemia with changed FLT3 gene where chemo is not an option due to old age/other conditions. Aims of this study: find suitable doses of gilteritinib, venetoclax and azacitidine as combined treatment; to learn how …

Basis: Evaluating Sirtuin Supplements To Benefit Elderly Trauma Patients (BES2T BET)

All genders
Phase 1
Adults 65 and older are more likely to have significant injuries from minor things like falls. They can have problems regaining strength due to sarcopenia (loss of muscle tissue as part of natural aging process). Nicotinamide riboside/pterstilbene (Basis) is commercially available nutraceutical. This randomized, double blind placebo controlled trial will …

QA test 20 feb 1

18 years - 100 years
Male
Phase 4
See protocol section 2 See protocol section 2 See protocol section 3 changed
 ConsCIOUS2: A Prospective Study of the Isolated Forearm Technique Commands  Long-term Sequelae and Electroencephalograph Correlates Following Laryngoscopy and Intubation in patients 18 - 40 years of age

ConsCIOUS2: A Prospective Study of the Isolated Forearm Technique Commands Long-term Sequelae and Electroencephalograph Correlates Following Laryngoscopy and Intubation in patients 18 - 40 years of age

All genders
This a multi-center prospective cohort study of a series of commands surveying responsiveness following laryngoscopy and intubation. Clinical care will not be controlled and will be left to local policy. We will also collect routinely recorded clinical data to frame the observations about IFT responsiveness (please see list below and …

Study to assess oral IPN60130 for the treatment of Fibrodysplasia Ossificans Progressiva (FOP) in male and female participants 5 years of age and older

5 years - 99 years
All genders
Phase 2
Interventional
The purpose of this study is to investigate the safety and efficacy of an investigational drug called IPN60130 in the treatment of FOP. IPN60130 is considered “investigational” because it has not been approved by the United States Food and Drug Administration (U.S. FDA) for the treatment of FOP.

Assessing the Efficacy and Safety of Staccato Alprazolam in Participants 12 Years of Age and Older with Stereotypical Prolonged Seizures

12 years - 99 years
All genders
Phase 3
Interventional
This research study is being conducted to learn how well Staccato Alprazolam works and how safe it is for the treatment of epilepsy. Some participants will receive a placebo.

Evaluating Study Drug Danicopan (ALXN2040) in Patients with Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)

70 years - 99 years
All genders
Phase 2
Interventional
This study will test danicopan, a new drug that is being developed by Alexion to slow down progression of GA. The goals of this study are as follows: • To find out whether danicopan can slow the rate of GA disease progression, and in turn slow the loss of visual …

A Phase 2a/b Randomized Double-blind Placebo-controlled Parallel Group Multicenter Clinical Study to Evaluate the Efficacy and Safety of OG-6219 in 3 Dose Levels in Women 18 to 49 Years of Age with Moderate to Severe Endometriosis-related Pain

All genders
A study to investigate efficacy and safety of OG-6219 BID in 3 dose levels compared with Placebo in participants aged 18 to 49 with moderate to severe endometriosis-related pain

Safety and Tolerability of TOP-N53 Applied on Digital Ulcers in Patients With Systemic Sclerosis (TOP-N53-02)

All genders
Phase 2
Interventional
The main goal of this clinical trial is to learn about how safe the new drug TOP-N53 solution is when it is applied to open wounds on the fingertip (digital ulcers) in people with an uncommon illness that results in hard, thickened areas of skin and additional problems with internal …
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