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Found 14 Depression trials

A listing of Depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Double-Blinded Randomized Crossover Trial of Stereoencephalography-Guided Multi-Lead Deep Brain Stimulation for Treatment-Refractory Obsessive Compulsive Disorder (SEEG-Guided DBS for OCD)

All genders
Phase 1
This dual-site, double-blinded, randomized, sham-controlled, crossover study is to assess the safety, feasibility, and preliminary efficacy of SEEG-guided multi-lead DBS in 10 participants suffering from severe symptoms of chronic, treatment-refractory OCD. Stage 1: Invasive SEEG Monitoring and Recovery Goal: To perform stimulation mapping studies and SEEG recordings, that aid in …
 Long-Term Follow-up of Older HIV-infected Adults in the ACTG: Addressing Issues of Aging  HIV Infection and Inflammation

Long-Term Follow-up of Older HIV-infected Adults in the ACTG: Addressing Issues of Aging HIV Infection and Inflammation

40 years - 99 years
All genders
Interventional
This study will look at the relationships between HIV infection, age and the immune system, and how these relate to the development of non-infectious illnesses such as heart disease, kidney disease, cancer, memory problems, and diabetes. Further, we will look at how demographic factors, behaviors, and social factors like social …

CART-38 in Adult AML and MM Patients - 1

All genders
Phase 1
Interventional
Primary hyperparathyroidism is a significant medical and public health problem in the world and affects approximately 100,000 new patients in the United States alone. If left untreated this can lead to renal stones, osteoporosis, fatigue, and depression. The best treatment for primary hyperparathyroidism is surgical parathyroidectomy. However surgical parathyroidectomy can …

An Adapted Friendship Bench for adolescents living with and at risk for HIV in Botswana: a mental health needs assessment and feasibility study

All genders
We will assess depression, anxiety, and substance use in adolescents at risk for a living with HIV. We will also assess the feasibility, acceptability and safety of a previously adapted version of the Friendship Bench (Bench). The Friendship Bench is a youth lay counsellor technique modelled after a previous study …
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