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Found 45 Rheumatoid Arthritis trials

A listing of Rheumatoid Arthritis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Evaluation of Long-Axial Field-of-View Positron Emission Tomography (PET) Scanner
18 years - 99 years
All genders
Normal 0 false false false EN-US X-NONE X-NONE The research study is being done to test the performance of a new type of whole-body imaging device called a Positron Emission Tomography (PET) long-axial field-of-view scanner, called the PennPET Explorer, that has been developed at the University of Pennsylvania and is …
 Phase II Trial of Pembrolizumab and Reirradiation in Bevacizumab Naive and Bevacizumab Resistant Recurrent Glioblastoma
18 years - 99 years
All genders
Phase 2
This is a multicenter, open-label, phase II trial of pembrolizumab plus re-irradiation among recurrent glioblastoma patients enrolled to two parallel, non-comparative treatment arms including patients who are bevacizumab naïve (Arm A, n=30) and patients who are bevacizumab-resistant (Arm B, n=30). All subjects must have histologically confirmed World Health Organization (WHO) …
 HOPE Trial
18 years - 99 years
All genders
HOPE is a randomized clinical trial that will evaluate approaches to reducing pain and opioid use among patients with chronic pain who are receiving maintenance hemodialysis for end-stage renal disease. The hypothesis is that pain coping skills training will be effective at reducing pain and opioid use, and that buprenorphine …
 Duration and Nature of Long-Term Immunosuppression After Neurosurgical Procedure
18 years - 99 years
All genders
Patients greater than 18 years of age undergoing a neurosurgical procedure at Penn Medicine will be approached for enrollment. Currently, this study is open only at the HUP and Penn Presbyterian Medical Center locations.Current research suggests that severe bodily stress caused by surgery may impair the immune system's ability to …
 A Randomized study of EHR Defaults and Using social Comparison feedback to Effectively decrease opioid prescription pill burden - The REDUCE Trial
99 years or below
All genders
Observational
Opioid-related abuse and overdose represent a growing national epidemic in the United States. Clinician practice patterns play an important role: opioid prescriptions impact the likelihood that patients will misuse or become dependent on these medications, with longer prescriptions leading to greater sustained use. In this study, we will evaluate a …
 Whole-Brain Spectroscopy Guided Personalized Delivery of Tumor Treating Fields in Glioblastoma Patients
22 years - 99 years
All genders
The research study is for Glioblastoma (GBM) patients beginning Optune, a therapy that uses - tumor treating fields (TTFields). As a part of this study participants will either receive Optune with standard treatment array mapping from MR imaging or an alternative treatment array mapping based on advanced MR imaging also …
 Treatment In Thoracic Aortic Aneurysm: Surgery versus Surveillance
18 years - 79 years
All genders
This study aims to compare the outcomes of patients undergoing early surgical intervention for ascending aortic aneurysms to those undergoing aneurysm surveillance. Patients with aneurysm diameters between 5.0 and 5.4 cm will be randomized to receive either medical therapy or elective surgery and will be followed annually for 5 years. …
 A Trial of Endocrine Response in Women with Invasive Lobular Breast Cancer
18 years - 99 years
All genders
Phase 2
To study whether fulvestrant is more effective than anastrozole or tamoxifen in reducing Ki67 in ILC and whether that Ki67 reduction will correlate with alterations in expression of ER and ER-regulated genes. Differential Ki67 effect in this study will serve as a surrogate for outcome of ILC patients on endocrine …
 AGIOS
18 years - 99 years
All genders
Phase 3
Normal 0 false false false EN-US X-NONE X-NONE  This research study is a phase 3, double-blind clinical trial to assess the efficacy of Agios versus placebo in subjects with residual or recurrent Grade 2 oligodendroglioma and astrocytoma with an IDH1 or IDH2 mutation who have undergone surgery as their only …
 Combination Ipatasertib and Atezolizumab to Prevent Recurrence in Triple Negative Breast Cancer
18 years - 99 years
All genders
Phase 2
The purpose of this study is to determine if a combination of two drugs, Ipatasertib and Atezolizumab, works as a treatment for residual cancer in breast or lymph nodes and have circulating tumor DNA in blood. Eligible subjects will be those with triple negative breast cancer.
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