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Found 21 Parkinson's Disease trials

A listing of Parkinson's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 To identify reliable markers of LRRK2 activity in human CSF.
30 years - 99 years
Accepts healthy volunteer
All genders
The purpose of this research study is to evaluate new tests for Parkinson's disease (PD) that may help in developing better treatments.
99 years or below
All genders
Phase 2
The main purpose of this study is to test the safety and efcacy (how well it works) of an experimental intervention called VY-AADC02 on the severity of PD. VY-AADC02 involves placing a gene in the brain that programs brain cells to produce an enzyme (protein) called AADC (aromatic amino acid …
99 years or below
All genders
Phase 2
The main purpose of this study is to test the safety and efficacy (how well it works) of an experimental intervention called VY-AADC02 on the severity of PD. VY-AADC02 involves placing a gene in the brain that programs brain cells to produce an enzyme (protein) called AADC (aromatic amino acid …
 Fixed-Dose Trial in Early Parkinson's Disease (PD) (TEMPO-1)
40 years - 80 years
All genders
Phase 3
Interventional
The purpose of this study is to evaluate the clinical efficacy, safety and pharmacokinetics of 2 fixed doses of tavapadon and placebo in participants with early Parkinson's Disease
18 years - 99 years
All genders
Interventional
Parkinson’s disease is a chronic disease of the nervous system that gets worse over time. Available treatments cannot stop or slow down the worsening over time. Some evidence suggests that people with Parkinson’s disease may have more inflammation in the brain. This is thought to be one of the reasons …
 A Clinical Study of NLY01 in Patient's With Early Parkinson's Disease
30 years - 80 years
All genders
Phase 2
This is a study designed to assess the safety, tolerability and efficacy of NLY01 in subjects with early untreated Parkinson's disease (PD). Evidence suggests NLY01, a pegylated form of exenatide, may be beneficial in Parkinson's disease and is being developed as a potential treatment for neurodegenerative disorders.
 The Parkinsons Progression Markers Initiative (PPMI) 2.0 Clinical - Establishing a Deeply Phenotyped PD Cohort
18 years - 99 years
Accepts healthy volunteer
All genders
The purpose of this study is to continue to obtain information from people with and without Parkinson disease (PD) so that researchers may better understand how Parkinson disease progresses, in order to inform better treatments. The information collected in this study is for research and not for clinical care. This …
 Healthy volunteers for Neuroinflammatory research study
18 years - 60 years
Accepts healthy volunteer
All genders
We are conducting research studies on how immune system cells contribute to inflammatory conditions of the nervous system, such as multiple sclerosis, neuromyelitis optica (NMO), encephalitis, head injury, epilepsy, Parkinson's disease (PD), Alzheimer's disease (AzD), Lou Gherig's disease (amyotrophic lateral sclerosis; ALS) frontotemporal dementia (FTD) and others. This includes investigating …
 Study in Parkinson Disease of Exercise
40 years - 80 years
All genders
Phase 3
Observational
The primary objective is to test whether the progression of the signs of Parkinson's disease is attenuated at 12 months in among persons who have not initiated medication for Parkinson Disease (PD) when they perform high-intensity endurance treadmill exercise.
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