Found 21 Parkinson's Disease trials
A listing of Parkinson's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The Parkinsons Progression Markers Initiative (PPMI) 2.0 Clinical - Establishing a Deeply Phenotyped PD Cohort
The purpose of this study is to continue to obtain information from people with and without Parkinson disease (PD) so that researchers may better understand how Parkinson disease progresses, in order to inform better treatments. The information collected in this study is for research and not for clinical care. This …
To identify reliable markers of LRRK2 activity in human CSF.
The purpose of this research study is to evaluate new tests for Parkinson's disease (PD) that may help in developing better treatments.
A Randomized Placebo Surgery Controlled Double-blinded Multi-center Phase 2 Clinical Trial Evaluating Efcacy and Safety of VY-AADC02 in Advanced Parkinsons Disease with Motor Fluctuations
The main purpose of this study is to test the safety and efcacy (how well it works) of an experimental intervention called VY-AADC02 on the severity of PD. VY-AADC02 involves placing a gene in the brain that programs brain cells to produce an enzyme (protein) called AADC (aromatic amino acid …
A Randomized Sham Surgery Controlled Double-blinded Multi-center Phase 2 Clinical Trial Evaluating the Efficacy and Safety of VY-AADC02 in Moderate to Advanced Parkinsons Disease with Motor Fluctuations
The main purpose of this study is to test the safety and efficacy (how well it works) of an experimental intervention called VY-AADC02 on the severity of PD. VY-AADC02 involves placing a gene in the brain that programs brain cells to produce an enzyme (protein) called AADC (aromatic amino acid …
A 6-month prospective randomized double-blind placebo-controlled clinical trial investigating the efficacy safety and tolerability of two different doses of buntanetap or placebo in patients with early Parkinsons disease
A double-blind study to investigate efficacy and safety of buntanetap compared with placebo in participants with early PD
Parkinsons Foundation PD GENEration Genetic Registry
This study aims to collect and share Parkinson’s disease genetic testing data from up to 500,000 study participants for research use. Participants will include people with Parkinson's disease (PD) and people at-risk for developing PD, and members of the general community that do not have PD. To investigate the genetic …
Post Market Clinical Follow Up Evaluating the Infinity Deep Brain Stimulation Implantable Pulse Generator System (PROGRESS)
You are being invited to participate in a research study because you have been diagnosed with Parkinson’s disease (PD) and you underwent or have been offered a procedure called Deep Brain Stimulation (DBS) as a treatment option to manage some of your symptoms of Parkinson’s disease. The purpose of this …
Study to determine the safety tolerability pharmacokinetics and pharmacodynamics of DNL201 in subjects with Parkinsons Disease
The purpose of this research is to investigate whether DNL201 (the study drug) is safe and tolerable in Parkinson’s disease patients and to investigate how DNL201 is absorbed, broken down, and eliminated from the body.
58-WEEK OPEN-LABEL TRIAL OF TAVAPADON IN PARKINSONS DISEASE (TEMPO-4 TRIAL)
The research study is being conducted to study of an investigational drug (referred to as “study drug” in this document) called CVL-751 (also known as Tavapadon) as a possible treatment for Parkinson’s disease. An investigational drug is one that has not been approved by the United States (US) Food and …
Study to Determine the Efficacy and Safety of BIIB122 in Participants with Parkinsons Disease
The LRRK2protein may contribute to disease progression in patients with PD.The study drug (BIIB122) is designed to affect the activity of LRRK2 protein in the brain and may prevent or delay the development of PD symptoms.The main purpose of this study is to look at whether the study drug works …
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