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Found 13 ny-neurosurgery trials

A listing of ny-neurosurgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 PD GPI MRFGUS
30 years - 100 years
All genders
To demonstrate ExAblate procedure is safe and works.There is evidence in medical literature showing that by ablating a particular cluster of cells in the brain, dyskinesia (abnormal movements)&motor symptoms of PD may improve. ExAblate can be used to perform ablation more precisely in minimally invasive fashion. In this study we …
18 years - 100 years
All genders
Phase 4
You are being invited to participate in a research study because you have been diagnosed with Parkinson’s disease (PD) and you underwent or have been offered a procedure called Deep Brain Stimulation (DBS) as a treatment option to manage some of your symptoms of Parkinson’s disease. The purpose of this …
 A Clinical Trial to Evaluate the Safety and Efficacy of Staged Bilateral Exablate Treatment of Medication Refractory Essential Tremor
99 years or below
All genders
The Exablate Model 4000 Type-1.0/1.1 Neuro system involves using an advanced, non-invasive technique currently approved by the Food and Drug Administration (FDA) to treat one side of your brain in a procedure called a thalamotomy (lesion the thalamus). This procedure involves performing an ablation (lesion) of an area of the …
 ONC201 in recurrent high-grade glioma
18 years - 99 years
All genders
Phase 2
This is a phase II, open-label study of ONC201 in adults with recurrent high- grade glioma. Subjects for this study will be recruited from the patient population that present to the Penn Brain tumor center- Department of Neurosurgery or Department of Medicine division of Hematology/ Oncology for evaluation and treatment …
 Study to Establish Image Interpretation Criteria for 18F Fluciclovine PET in Detecting Recurrent Brain Metastases
18 years - 99 years
All genders
Phase 2
Interventional
The overall objectives of the study is to establish visual image interpretation criteria for 18F-fluciclovine PET in detecting recurrent brain metastases and to establish other image interpretation criteria for 18F-fluciclovine PET in detecting recurrent brain metastases.
 ImmuneSense Study- Safety and Efficacy of IGV-001  an Autologus Cell Immunotherapy With Antisense Oligonucleotide (IMV-001) Targeting IGF-1R  in Newly Diagnosed Patients With Glioblastoma Multiforme
18 years - 99 years
All genders
Phase 2
The purpose of this study is to see how safe the study medicine, IGV-001 plus standard of care (SOC), is and to compare IGV-001 with placebo (only standard of care) to see if it works in slowing GBM tumor regrowth. Participants for this study will be recruited from the patient …
 GGDEF-32 Trident
99 years or below
All genders
The primary objective is to determine if TTFields to the brain concomitantly with RT and TMZ in the treatment of GBM patients prolongs the overall survival of patients, compared to RT and TMZ followed by TTFields and maintenance TMZ. Secondary objectives assess progression-free survival, 1 and 2 year survival rates, …
 MT-3921- Phase 2  Study to Assess the Efficacy and Safety of MT-3921 in Subjects with Acute Traumatic Cervical Spinal Cord Injury
18 years - 70 years
All genders
Phase 2
MT-3921 is an investigational monoclonal antibody therapy for patients with severe (AIS grade A-C) traumatic cervical spinal cord injury (SCIs). This study aims to compare the efficacy of MT-3921 to a placebo with regard to improving patients sensory and motor function and overall quality of life. Additionally this study aims …
18 years - 75 years
All genders
Phase 2
This is a multicenter, randomized, open-label study of Toca 511 and Toca FC versus standard of care (SOC) that comprises Investigators choice of either single agent chemotherapy (lomustine or temozolomide) or bevacizumab administered to subjects undergoing resection for first or second recurrence (including this recurrence) of glioblastoma or anaplastic astrocytoma. …
 A Randomized Multicenter Phase 2 Study of DSP-7888 Dosing Emulsion in Combination with Bevacizumab versus Bevacizumab Alone in Patients with Recurrent or Progressive Glioblastoma following Initial Therapy
18 years - 98 years
All genders
Phase 2
The BBI-DSP-7888-201G trial is designed to compare the overall survival (OS) between treatment with DSP-7888 Dosing Emulsion plus bevacizumab (Bev) versus Bev alone in patients with recurrent or progressive glioblastoma multiforme (GBM) following initial therapy. This is a randomized, active-controlled, multicenter, open-label, parallel groups, Phase 2 study. Approximately 200 patients …
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