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Found 22 abramson-cancer-center trials

A listing of abramson-cancer-center medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Trial of ASP-1929 Photoimmunotherapy Versus Physician's Choice Standard of Care for the Treatment of Locoregional  Recurrent Head and Neck Squamous Cell Carcinoma
18 years - 99 years
All genders
Phase 3
This is a Phase 3, randomized, double-arm, open-label trial of ASP-1929 photoimmunotherapy (ASP-1929 PIT) versus physician's choice standard of care (SOC) for the treatment of locoregional, recurrent head and neck squamous cell carcinoma (HNSCC) in patients who have failed or progressed on or after at least two lines of therapy, …
18 years or above
All genders
Observational
This study investigates the use of short femoral stems in hip arthroplasty for patients with primary hip osteoarthritis or osteonecrosis. The purpose of this study is to evaluate the outcomes when these stems are implanted through a minimally invasive anterior approach.The study focuses on understanding the safety and effectiveness of …
40 years - 75 years
Accepts healthy volunteer
Female
500 patients will be prospectively recruited to undergo a fast breast MRI examination. The women will be recruited for the study will meet the following criteria: 1. African American 2. negative DBT examination 11 months prior to recruitment 3. Heterogeneously and Extremely breast densities 4. clinically asymptomatic- no palpable masses, …
21 years or above
Accepts healthy volunteer
All genders
This study investigates harm-reduction sampling for cigarette smokers who are not currently motivated to quit. The focus is on comparing the effects of different harm-reduction products to medicinal nicotine on smoking behavior.The purpose is to evaluate the impact of offering choices among harm-reduction products and to understand the mechanisms and …
18 years or above
Male
Phase 3
Interventional
This study investigates prostate cancer that has returned after surgery. The purpose is to see if adding investigational medication and targeted radiation to standard treatment works better for patients with a rise in PSA levels after prostate cancer surgery.The study focuses on evaluating the effectiveness of additional treatments based on …
 EA2174: A Phase II/III Study of Peri-operative Nivolumab and Ipilimumab in Patients with Locoregional Esophageal and Gastroesophageal Junction Adenocarcinoma
18 years - 99 years
All genders
Phase 3
This phase II/III trial studies the usefulness of treatment with nivolumab and ipilimumab in addition to standard of care chemotherapy and radiation therapy in patients with esophageal and gastroesophageal junction adenocarcinoma who are undergoing surgery. This trial is open to Penn Medicine's Abramson Cancer Center patients only. Please contact the …
 KEYMAKER-U02- substudy 02B
18 years - 99 years
All genders
Phase 1
Patients from Penn Medicine's Abramson Cancer Center will be approached for participation.This sub-study is part of a larger research study that is testing experimental treatments for melanoma. Various study drugs will be tested in combination with pembrolizumab in this study. Treatment groups include: a) MK-7684 and pembrolizumab b) pembrolizumab alone …
 KEYMAKER-U02
18 years - 99 years
All genders
Phase 1
Interventional
Patients will be recruited from within the Penn Medicine Abramson Cancer Center pool of patients. This sub-study is part of a larger research study that is testing experimental treatments for melanoma. This sub-study is testing experimental drugs when they are given before and/or after melanoma surgery. Subjects will be assigned …
 Measurement of B cell maturation antigen-Directed CAR T Cells During TAK-573 Study Participation
1 years - 99 years
Male
Interventional
The primary objective of this pilot study is to explore in a preliminary fashion whether administration of TAK-573 increases the number of BCMA-specific T cells in blood samples from patients with myeloma.
 Tissue Collection for Multiple Myeloma Research
18 years - 99 years
All genders
Interventional
The primary purpose of this research study is to obtain specimens (blood, bone marrow, and other tissues) for research about multiple myeloma and related diseases.
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