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Found 386 oncology trials

A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Evaluation of Outcomes from Treatment of Benign or Malignant Gastroesophageal Diseases

All genders
Observational
This study will be a retrospective chart review of patients who have been diagnosed with benign or malignant pancreatic disease under the practice of Dr. Rohan Jeyarajah, M.D., Dr. Houssam Osman M.D., and Dr. Edward Cho M.D., Sc.M. at Methodist Health System Hospital in Richardson, Texas. The Investigators plan to …

Radiation Oncology Registry and Biosample Repository

18 years - 99 years
All genders
Observational
The goal of this study is to establish a registry and biosample repository (defined as blood, urine, and tumor specimens in patients with a pathologically confirmed diagnosis of neoplasia receiving radiotherapy or photodynamic therapy (PDT). Radiation Oncology Registry (Required): The first part of this study is the Radiation Oncology Registry. …

A Phase 1/2a Open-Label Safety Pharmacokinetic and Preliminary Efficacy Trial of Oral ATRN-119 in Patients with Advanced Solid Tumors (AR-276-01)

All genders
Phase 1
The study will evaluate the safety profile of escalating doses of continuous daily oral ATRN-119 and to determine the maximum tolerated dose (MTD) and recommended dose. ATRN-119 is a drug that has been developed to treat cancers by taking advantage of genetic mutations found only in the tumor and not …

NP-G2-044 as Monotherapy and Combination Therapy in Patients With Advanced or Metastatic Solid Tumor Malignancies

All genders
Phase 1
NP-G2-044 Monotherapy Primary Objectives The primary objectives for patients receiving NP-G2-044 monotherapy are the following: - To identify the recommended Phase 2 dose (RP2D) of continuously dosed NP-G2-044 monotherapy (Mono-RP2D) and characterize its safety; and - To assess preliminary signals of NP-G2-044 anti-tumor efficacy when administered as continuously dosed monotherapy. …
 Radiation Oncology Registry

Radiation Oncology Registry

18 years - 99 years
All genders
You are being asked to participate in the Radiation Oncology Registry. Participation in this study requires no additional obligations on your part; your participation means you are granting permission for your doctors to extract information from your medical chart and use this data for research purposes. Should any findings from …

A Prospective Multicenter Study of Transbronchial Microwave Ablation Using Robotic-Assisted Bronchoscopy in Subjects with Oligometastatic Tumors in the Lung

All genders
The primary objective of the study is to evaluate the safety and effectiveness of the NEUWAVETM FLEX MC Microwave Ablation System and Accessories used in transbronchial ablation procedures for adult subjects with oligometastatic tumors ( 2cm) in the lung. Technique Efficacy: Ablation of the target tumor(s) with the ablation zone …
 Study to Evaluate Imaging Feasibility,  Safety and Diagnostic Performance Post Dosing of an Intraoperative Fluorescent Imaging Agent for Detection of Metastatic Lymph Nodes  Primary Tumors and Tumor Margins in Patients with Solid Tumors

Study to Evaluate Imaging Feasibility, Safety and Diagnostic Performance Post Dosing of an Intraoperative Fluorescent Imaging Agent for Detection of Metastatic Lymph Nodes Primary Tumors and Tumor Margins in Patients with Solid Tumors

18 years - 99 years
All genders
Phase 2
The purpose of this research study is to learn about the safety and effectiveness of using ONM 100 to obtain images of primary tumors and metastatic lymph nodes in patients with solid tumors undergoing routine surgery. Adults at least 18 years of age with a Biopsy-confirmed diagnosis of primary or …

Monitoring Disease Burden and Biology Using Tumor Cell Free DNA in Metastatic Kidney Cancer

All genders
Blood is an easily accessible source of tumor cell free (cf) DNA. Both normal and malignant cells shed DNA into the circulation, and advanced genomics technologies can analyze tumor cfDNA, making blood a source of real-time genomic tumor profiling. For ccRCC patients, peripheral blood will be obtained as part of …
 CEA for the delineation of primary and recurrent tumor and metastases in patients undergoing curative surgery for colorectal cancer

CEA for the delineation of primary and recurrent tumor and metastases in patients undergoing curative surgery for colorectal cancer

All genders
Phase 3
SGM-101 is a fluorochrome-labeled anti-carcino-embryonic antigen (CEA) monoclonal antibody. What this means is that part of SGM-101 is a chemical that is attracted to and will attach to the cells of your cancer. Another part of SGM-101 is a chemical that will glow when infrared light is shined on it. …

A Phase 1 Open-Label Safety Pharmacokinetic and Preliminary Efficacy Study of STRO-002 An Anti-Folate Receptor alpha Antibody- Drug Conjugate (ADC) In Patients with Advanced Epithelial Ovarian Cancer (including Fallopian Tube or Primary Peritoneal Cancers) and Endometrial Cancers

All genders
Phase 1
This study has two parts: Part 1 (dose escalation) and Part 2 (dose expansion). The purpose of Part 1 is to determine: What effects, good and/or bad, STRO-002 has on subjects and their disease The highest dose of STRO-002 that can be safely given to subjects using a pre-defined starting …
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