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Found 356 oncology trials

A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 FES PET/CT in Endocrine Refractory Breast Cancer
18 years - 99 years
All genders
Patients with recurrent or metastatic ER+ breast cancer, who have failed prior endocrine therapy may be eligible for this study.  Patients may participate in this study, if they are at least 18 years of age, most participants will be receiving care at the clinical practices of the University of Pennsylvania. …
99 years or below
All genders
To achieve all of our research objectives, we plan to conduct a pilot study of a CDS intervention, exposing half of our clinician sample to the TUT Service+VM condition during cancer care workflow, and comparing important outcome measures to those observed among the half exposed to the current usual care …
 REVITALIZE: A Telehealth Intervention for Women with Advanced Ovarian Cancer and Inhibitor-Related Fatigue
18 years - 99 years
Female
Interventional
In this study, we are comparing the use of two different interventions, 1) a 6 week skills-based telehealth intervention that provides participants with support, knowledge, and skills for coping with fatigue, or 2) educational materials and resources, to help you manage your fatigue.
 Treatment of Milademetan Versus Trabectedin in Patient With Dedifferentiated Liposarcoma (MANTRA)
18 years - 99 years
All genders
Phase 3
Interventional
Randomized, multicenter, open-label, Phase 3 registration study designed to evaluate the safety and efficacy of milademetan compared to trabectedin in patients with unresectable or metastatic DD liposarcoma that progressed on 1 or more prior systemic therapies.
 Innovative Combination Immunotherapy for Metastatic Triple Negative Breast Cancer (TNBC)
18 years - 99 years
Female
Phase 2
This phase II trial studies how well avelumab in combination with binimetinib, utomilumab, or anti-OX40 antibody PF-04518600 works in treating patients with triple negative breast cancer that is stage IV or is not able to be removed by surgery (unresectable) and has come back (recurrent). Immunotherapy with checkpoint inhibitors like …
18 years - 75 years
All genders
Phase 2
This is a multicenter, randomized, open-label study of Toca 511 and Toca FC versus standard of care (SOC) that comprises Investigators choice of either single agent chemotherapy (lomustine or temozolomide) or bevacizumab administered to subjects undergoing resection for first or second recurrence (including this recurrence) of glioblastoma or anaplastic astrocytoma. …
 Study of AVB-S6-500 plus Nab-paclitaxel and Gemcitabine in Patients with Locally Advanced or Metastatic Pancreatic Adenocarcinoma
18 years - 99 years
All genders
Phase 1
Interventional
The purpose of this research study is to evaluate the safety, tolerability and efficacy of AVB-S6-500 combined with chemotherapies called nab-paclitaxel and gemcitabine in subjects with pancreatic cancer who have not received treatment previously.
 RADVAX FOR RELAPSED/REFRACTORY NON-HODGKIN LYMPHOMA: A PHASE II TRIAL OF PEMBROLIZUMAB + LOW DOSE RADIOTHERAPY
18 years - 99 years
All genders
Phase 2
This study plans to treat subjects with pembrolizumab by infusion in combination with radiation therapy to see if the combination is an effective treatment for relapsed/refractory non-Hodgkin lymphoma. Radiation therapy is commonly used to treat relapsed/refractory non-Hodgkin lymphoma. Although pembrolizumab is FDA-approved for some cancers, including Hodgkin lymphoma, it is …
18 years - 99 years
All genders
Phase 2
Interventional
The purpose of this study are to determine the maximum dose of FF-10832 that can be tolerated when taken in combination with pembrolizumab and to determine whether FF10832 taken by itself or in combination with pembrolizumab has anti-tumor activity.
 Technology for Detection of SARS-Cov-2 in HIV-Positive Cancer Patients
99 years or below
All genders
The main purpose of this study is to try a new type of laboratory test for COVID-19 (also called SARS-CoV-2 or novel coronavirus).  COVID-19 is a new disease, so not enough is known about it yet.  This study hopes to collect more information about who is most as risk from …
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