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Found 356 oncology trials

A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Study to Evaluate Imaging Feasibility,  Safety and Diagnostic Performance Post Dosing of an Intraoperative Fluorescent Imaging Agent for Detection of Metastatic Lymph Nodes  Primary Tumors and Tumor Margins in Patients with Solid Tumors
18 years - 99 years
All genders
Phase 2
The purpose of this research study is to learn about the safety and effectiveness of using ONM 100 to obtain images of primary tumors and metastatic lymph nodes in patients with solid tumors undergoing routine surgery. Adults at least 18 years of age with a Biopsy-confirmed diagnosis of primary or …
 An Open-Label  Safety and Tolerability Phase 1b Trial of CAN04  A Fully Humanized Anti-IL1RAP Monoclonal Antibody  in Combination with Pembrolizumab in Subjects with Solid Tumors Progressing on PD-1/PD-L1 Inhibitor-Containing Regimens
99 years or below
All genders
Phase 1
This study will consider the safety and effectiveness of a study drug, CAN04, in combination with pembrolizumab, in the treatment of incurable or metastatic non-small-cell lung cancer, head and neck squamous cell carcinoma, urothelial cancer, or malignant melanoma. The study aims to establish a recommended dose of CAN04 in combination …
 Study of the Safety  Pharmacokinetics  Pharmacodynamics  and Preliminary Clinical Activity of RP-6306 in Patients with Advanced Solid Tumors (MYTHIC Study)
12 years - 99 years
All genders
Phase 1
The primary purpose of this study is to assess the safety and tolerability of an Investigational drug in patients with eligible advanced solid tumors, determine the maximum tolerated dose (MTD) and assess preliminary anti-tumor activity.
 CEA for the delineation of primary and recurrent tumor and metastases in patients undergoing curative surgery for colorectal cancer
99 years or below
All genders
Phase 3
SGM-101 is a fluorochrome-labeled anti-carcino-embryonic antigen (CEA) monoclonal antibody. What this means is that part of SGM-101 is a chemical that is attracted to and will attach to the cells of your cancer. Another part of SGM-101 is a chemical that will glow when infrared light is shined on it. …
 Adjuvant Nivolumab in Resected Lung Cancers (ANVIL)  A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-Small Cell Lung Cancers
99 years or below
All genders
Phase 3
The purpose of this study is to find if adding the study drug, nivolumab (also known as OPVIDO), will limit lung cancer from growing back in patients with early stage non-small cell lung cancer. Nivolumab is a drug that may turn on the body's immune system to attack any cancer …
 A Pilot Study of Diffusion Weighted MRI to Assess Esophageal Tumor Response to Neoadjuvant Chemoradiation
99 years or below
All genders
Phase 1
The purpose of this study is to determine if a particular Magnetic Resonance Imaging (MRI) called Diffusion Weighted (dwMRI)) will detect changes in your tumor before and during treatment with chemotherapy and radiation for esophageal cancer. We used the dwMRI because it has been used in other types of cancers …
 Patients Who Have Completed a Previous Oncology Study With Olaparib (ROSY-O)
18 years - 99 years
Female
Prior participants of ROSY-O study
99 years or below
All genders
Phase 1
The purpose of this Study is to test the safety and tolerability of the INCB086550 and to find out what effects, if any, the INCB086550 has on people and their cancer. The INCB086550 has been tested in animals but not yet in people. This Study will test different doses of …
 Intramolecular Imaging with ICG (PRIME)
18 years - 99 years
All genders
Phase 2
Interventional
The purpose of this protocol is to monitor the rate of recurrence in patients who undergo cancer surgery. Patient diagnosed with solid tumor cancers have a high rate of recurrence when surgery is a treatment. The high rates of recurrence suggest that surgeons are unable to completely detect and remove …
 LODESTAR: Study of Rucaparib as Treatment for SoliD Tumors Associated with DEleteriouS MuTations in Homologous RecombinAtion Repair Genes
18 years - 99 years
All genders
Phase 2
This is a Phase 2 multicenter, open-label study evaluating rucaparib as treatment for solid tumors associated with a deleterious mutation in Homologous Recombination Repair (HRR) genes. All patients will be required to have received prior treatment with at least 1 line of life-extending therapy (if available) or have a tumor …
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