Found 356 oncology trials
A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The purpose of this study is to identify recommended Phase 2 doses (RP2Ds) for each treatment combination (between daratumumab plus talquetamab and teclistamab plus daratumumab) and to characterize the safety of each RP2D for selected treatment combinations. Patients from within the Penn Medicine Cancer Center will be approached as potential participants.
We want to study the effects of immune therapy for cancer on the normal immune system. Some of the cells of the immune system reside in the bone marrow, and can only be obtained by inserting a needle into the bone marrow (typically done through the back of the hip …
We would like to rely on the Fred Hutchinson Cancer Research Center (FHCRC) as IRB of record for this study. We are doing this study to examine ways to improve the health of long-term survivors of bone marrow or blood stem cell transplant. We want to know if an online …
The basic premise of this pilot study is to enroll 40 patients over 1.5 years who have Stage III or IV non-small cell lung cancer and are planned for definitive treatment with concurrent chemoradiation when a contrast-enhanced 4DCT is planned. The primary goal is to quantify the reproducibility of lung …
Patients from Penn Medicine's Abramson Cancer Center will be approached for participation.This sub-study is part of a larger research study that is testing experimental treatments for melanoma. Various study drugs will be tested in combination with pembrolizumab in this study. Treatment groups include: a) MK-7684 and pembrolizumab b) pembrolizumab alone …
Patients will be recruited from within the Penn Medicine Abramson Cancer Center pool of patients. This sub-study is part of a larger research study that is testing experimental treatments for melanoma. This sub-study is testing experimental drugs when they are given before and/or after melanoma surgery. Subjects will be assigned …
STAGE 1: This is an open-label safety study of enobosarm 9 mg QD coadministered with a CDK 4/6 inhibitor (abemaciclib), 150 mg BID. STAGE 2: This study is a multicenter, randomized, open-label, two treatment arm, efficacy and safety study. Subjects will be randomized to the two treatment arms (Enobosarm Combination …
The purpose of this Treatment Plan is to allow access to tisagenlecleucel (CTL019) for eligible patients diagnosed with acute lymphoblastic leukemia (ALL) or large b-cell lymphomas who are unable to receive commercially manufactured product due to failure of the incoming apheresis material or outgoing product to meet the commercial specifications …
This research is a sub-study to the “Understanding influenza vaccine responses in the setting of immunotherapy” protocol (parent study). This sub-study is open to only those participants that have consented to be part of the above parent study. This study is designed to better understand antibody responses in the setting …
The purpose of this study is to see if the investigational drug, selinexor, has any effects in eligible participants with advanced unresectable dedifferentiated liposarcoma (DDLS). Selinexor will be given at a fixed oral dose of 60mg or placebo twice weekly on Days 1 and 3 during Weeks 1-6 of each …
