Found 30 cardiology trials
A listing of cardiology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
A Randomized Study to Evaluate the Efficacy and Safety of ION-682884 in Patients with Hereditary Transthyretin-Mediated Amyloid Polyneuropathy
A Phase 3 Global, Open-Label, Randomized Study to Evaluate the Efficacy and Safety of ION-682884 in Patients with Hereditary Transthyretin-Mediated Amyloid Polyneuropathy. For those with : a. Stage 1 or Stage 2 according to the Familial Amyloid Polyneuropathy (FAP) or Coutinho Stage b. Documented genetic mutation in the TTR gene …
Prospective evaluation of the durability of aortic bioprostheses/valves with RESILIA tissue (RESILIENCE Trial)
The objective of this observational trial is to determine time to valve failure due to valve deterioration requiring re-intervention and collect/investigate early potential predictors of valve durability (e.g., calcification and hemodynamic deterioration) in RESILIA tissue valves.
DCPMS: Dialated Cardiomyopathy Precision Medicine Study
This study aims to understand the effects of potential familial/genetic links in an otherwise unclear origin of a patient's heart disease.
Electrogram Guided Myocardial Advanced Phenotyping (EMAP) Study for patients recently diagnosed with cardiomyopathy
This study is enrolling newly diagnosed heart failure (within 6 months from diagnosis) patients with no known cause for their heart disease. We are utilizing already used technology, voltage mapping capabilities used in electrophysiology procedures, to more directly target weaker areas of the left and right ventricles. our physicians would …
LIFE Study: Entresto TM in Advanced Heart Failure
This study aims to understand the benefits/risks of Entresto in NYHA III-IV patients.
Prospective 4D Computed Tomography Angiography Of The Bicuspid Aortic Valve Apparatus: A Comparison Of Bicuspid Aortic Valves With And Without Aortic Insufficiency
The purpose of this study is to characterize the differences in the aortic valve and aortic root anatomy in patients with BAVs in order to better understand the anatomical features that allow the BAV to function normally. With this information, surgeons and cardiologists will be better able to determine which …
Cardiometabolic Effects of Dipeptidyl Peptidase IV and Related Pathways
DPP4 is an enzyme that breaks down proteins that may affect blood sugar and the heart. We will recruit individuals from the Penn Biobank (cases, controls). Participants will be asked to complete a meal test, DXA, and echocardiogram with exercise. A cardiac MRI and related pilot study are optional.
Repeatability Reproducibility and Efficacy Testing of Automated Hemodynamic Output by Transthoracic Echocardiography
This study will involve scanning of a patient's chest wall with an approved ultrasound device (Lumify) to obtain images prior to a patient undergoing cardiac surgery. The investigational device involved in this study will be the software that automatically outputs heart data from those chest wall images (Automated Hemodynamics Application).
Implantation of the HeartMate 3 in Subjects with Heart Failure
This is a prospective, post-market, multi-center, non-blinded, single arm study of the HeartMate 3 Left Ventricular Assist System (LVAS). The objective of this study is to evaluate the implantation of the HM3.
A Study to Evaluate Patients with TransthyretinMediated Amyloid Cardiomyopathy (ATTR CM)
This study is for those diagnosed with transthyretin-mediated amyloid cardiomyopathy which is a disease caused by change in a protein called transthyretin (TTR). This change can either be sporadic which is known as wild-type (wtATTR-CM) or due to a mutation of the TTR gene which is hereditary (hATTR-CM). In both …
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