Found 30 cardiology trials
A listing of cardiology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Featured study
This study investigates hereditary transthyretin-mediated amyloid polyneuropathy, focusing on evaluating the safety and efficacy of an investigational medication for treating this condition.Who can participate: Adults aged 18 to 82 with Stage 1 or Stage 2 Familial Amyloid Polyneuropathy, a genetic mutation in the TTR gene, and symptoms of neuropathy can …
Featured study
The objective of this observational trial is to determine time to valve failure due to valve deterioration requiring re-intervention and collect/investigate early potential predictors of valve durability (e.g., calcification and hemodynamic deterioration) in RESILIA tissue valves.
Featured study
This study aims to understand the effects of potential familial/genetic links in an otherwise unclear origin of a patient's heart disease.
Featured study
This study is enrolling newly diagnosed heart failure (within 6 months from diagnosis) patients with no known cause for their heart disease. We are utilizing already used technology, voltage mapping capabilities used in electrophysiology procedures, to more directly target weaker areas of the left and right ventricles. our physicians would …
Featured study
This study aims to understand the benefits/risks of Entresto in NYHA III-IV patients.
The purpose of this study is to characterize the differences in the aortic valve and aortic root anatomy in patients with BAVs in order to better understand the anatomical features that allow the BAV to function normally. With this information, surgeons and cardiologists will be better able to determine which …
DPP4 is an enzyme that breaks down proteins that may affect blood sugar and the heart. We will recruit individuals from the Penn Biobank (cases, controls). Participants will be asked to complete a meal test, DXA, and echocardiogram with exercise. A cardiac MRI and related pilot study are optional.
This study will involve scanning of a patient's chest wall with an approved ultrasound device (Lumify) to obtain images prior to a patient undergoing cardiac surgery. The investigational device involved in this study will be the software that automatically outputs heart data from those chest wall images (Automated Hemodynamics Application).
This is a prospective, post-market, multi-center, non-blinded, single arm study of the HeartMate 3 Left Ventricular Assist System (LVAS). The objective of this study is to evaluate the implantation of the HM3.
This study is for those diagnosed with transthyretin-mediated amyloid cardiomyopathy which is a disease caused by change in a protein called transthyretin (TTR). This change can either be sporadic which is known as wild-type (wtATTR-CM) or due to a mutation of the TTR gene which is hereditary (hATTR-CM). In both …
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