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Found 13 pe-pediatrics trials

A listing of pe-pediatrics medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Chronic insomnia and CSF markers of dementia
30 years - 59 years
All genders
The purpose of this study is to identify the relationship between chronic sleep disturbance and proteins in spinal fluid that are related to dementia and a molecule called orexin that helps regulate wakefulness and appetite in the brain. Individuals with sleep problems and good sleepers will be asked to participate.
 The Diaphragmatic Initiated Ventilatory Assist (Diva) Trial
99 years or below
All genders
Interventional
DIVA is a pragmatic randomized clinical trial (RCT) to determine: among (P) preterm infants born 24-27 6/7 weeks gestation undergoing extubation from mechanical ventilation, whether (I) Non-invasive neurally adjusted ventilatory assist (NIV-NAVA) (C) compared with Non-synchronized nasal intermittent positive pressure ventilation (NS-NIPPV), will reduce the incidence of (O) extubation failure …
 Autism Spectrum Program of Excellence
3 years - 99 years
All genders
The goal of the ASPE study is to investigate the genetic basis of Autism spectrum disorder (ASD) and autism-related traits.Individuals 3 years old or older with a diagnosis (or suspected diagnosis) of autism spectrum disorder without intellectual disability may be eligible to participate. We are also recruiting individuals with a deletion or …
 Gene Transfer for Patients With Sickle Cell Disease Using a Gamma Globin Lentivirus Vector
18 years - 99 years
All genders
Phase 1
This Phase 1/2 study will use a novel therapy, ARU-1801, for Sickle Cell Disease, using gene transfer of recombinant -globin lentivirus (LV) vector. The purpose of this study, which involves research, is to determine whether an experimental procedure called “gene transfer” is safe and effective. If you are interested in …
 Social Functioning in Adult Autism
16 years - 99 years
All genders
This project will  test the effectiveness of a new program to improve social functioning in adults with autism spectrum disorder (ASD).
 The Whole Health Study: Collaborative Care for OUD and Mental Health Conditions: Randomized Trial
18 years - 99 years
All genders
We are interested in comparing 3 care conditions to determine which condition is best to help people with opioid use disorder (OUD) and mental illness reduce their drug use and improve their psychiatric symptoms. The model we are testing is called collaborative care. This model uses a team-based approach in …
 Myeloid derived suppressor cell expression in newborn infants: an observational cohort study
1 years - 1 years
All genders
This research study is being conducted to study a type of white blood cells called MDSC in newborn babies. These cells help regulate our body’s immune system. Learning more about these cells may help us to better understand immune function in newborn babies.
 The NICU Antibiotics and Outcomes Trial (NANO)
99 years or below
All genders
The goal of the NANO trial is to study the longstanding clinical practice of empirically administering intravenous antibiotics to extremely low birthweight (ELBW) infants in the first days of life. In this 802-subject multicenter placebo-controlled randomized clinical trial, the hypothesis to be tested is that the incidence of adverse outcomes …
25 years - 65 years
All genders
Interventional
This is a study that evaluates SAGE-718 in participants with Huntington's Disease.
 A Trial of Endocrine Response in Women with Invasive Lobular Breast Cancer
18 years - 99 years
All genders
Phase 2
To study whether fulvestrant is more effective than anastrozole or tamoxifen in reducing Ki67 in ILC and whether that Ki67 reduction will correlate with alterations in expression of ER and ER-regulated genes. Differential Ki67 effect in this study will serve as a surrogate for outcome of ILC patients on endocrine …
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