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MRI and Biological Markers of Acute E-Cigarette Exposure in Smokers and Vapers

This research study is being conducted to examine the effects of electronic cigarette aerosol, in the presence and absence of nicotine, on the endothelium, a layer of cells that act as a protective barrier and play an important part in controlling the flow of blood around the body.
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Detailed Description

Smokers and vapers: This group will complete three study visits. During each visit blood is drawn twice, an MRI is performed twice, and a smoking challenge is completed. No more than 30, and no fewer than 3 days can pass between each visit. A parking voucher and monetary compensation will be provided for each visit ($150 for every visit completed, $450 in total). 

Nonsmokers: This group will complete one study visit during which blood is drawn once, one MRI is performed, and a hematocrit measurement is taken. A parking voucher and monetary compensation will be provided ($100 for one visit).

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Call 1800-9860-568 now to find out if you are eligible.

Age
18 - 45
Gender
All
NCT ID
850432
Phase
-1
Status
Recruiting Now
Medical Condition
smokers

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Medical Condition
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The Study
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About Clinical Trials
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Your Journey

01
Receiving the medication
You would receive etanercept (Enbrel) twice a week for 12 weeks and then once a week for 12 weeks. Etanercept, as well as study related medical care, is provided at no cost.
02
Visiting the study site
Study participation involves approximately 8 visits to your local study center over 6 to 7 months.
03
Follow-up
There would also be a follow-up telephone call 30days after completing the study. No visits are required after participation is complete.

Call 1800-9860-568 now to find out if you are eligible.