Neuropsychological Assessment of Remediation for Cognitive Impairments in

Recruiting

18 years - 60 years

All

Phase N/A

70 participants needed

2 Locations

Brief description of study

This study evaluates the effect of a cognitive remediation program on neurocognitive, social cognitive and metacognitive functions designed for patients living with a schizophrenia spectrum disorder.

Detailed description of study

Evaluation of the specific therapeutic efficacy of the ecological cognitive remediation program for schizophrenia spectrum disorder [ECo-Sz] on neurocognitive deficits, social cognition deficits and metacognition deficits of patients with a schizophrenia spectrum disorder.

In this double-blind (patients, outcomes assessors) controlled randomized trial the investigators compare patients receiving Ecological Cognitive training program for schizophrenia spectrum disorder [ECo-Sz] to patients benefiting from recovery-oriented therapy [ThOR]. Patients are treated for two months and monitored for four months.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

Conditions: Schizophrenic Disorders
Age: 18 years - 60 years
Gender: All

Inclusion Criteria:

Schizophrenia Disorder diagnosis, according to Diagnostic and Statistical Manual of mental disorders - Fifth edition (DSM-V) - Patient stabilized in terms of positive and negative symptomatology (absence or presence of weak positive and negative symptoms)
Positive and Negative stable symptoms (no or few positive and negative symptoms)
Stable and effective minimum dose of medication (antipsychotic) for the last three months
Cognitive complaint expressed by the patient
Informed consent form read, initialed and signed
Understanding of spoken and read French
Patient registered on the social welfare system

Exclusion Criteria:

Other diagnosis at the forefront than Schizophrenia of the DSM-V
Medical history neurological disorder resulting in hospitalization
Acute episode in the last three month
Somatic disorders resulting in cognitive impairment
Engagement in a research protocol either currently or over the last month
Neuropsychological assessment evaluation during the last six month
Patients under the protection of a conservator (simple or reinforced)
Individuals in vulnerable circumstances

Updated on 02 Aug 2026. Study ID: 10477M-NARCIS

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