Comparison of Surgery and Medicine on the Impact of Diverticulitis (COSMID) Trial

COSMID is a pragmatic, patient-level randomized superiority trial of elective colectomy vs. best medical management for patients with quality of life (QoL) limiting diverticular disease. The goal of the COSMID trial is to answer the question: For patients with QoL-limiting diverticular disease, is elective colectomy more effective than best medical management? Participants will be paid up to $180. Inclusion Criteria 1. Adults ≥18 years 2. At least one episode of diverticulitis confirmed by CT scan in last 5 years and a colonoscopy to rule out or screen for other colon pathology concordant with screening guidelines; And A. History of recurrent uncomplicated diverticulitis without current symptoms (AUD in remission) over the prior 5 years; or B. Persistent signs, symptoms, and concerns related to diverticular disease ≥3 months after recovery from an episode of AUD (e.g., excluding irritable bowel syndrome and other conditions in coordination with gastroenterologist)

You may be eligible for this study if you meet the following criteria:

• Conditions: Medical Research, Diverticulitis
• Age: 18 years - 50 years
• Gender: All