Build status - In Progress

CILT + HD-tDCS as a Potential Treatment for Primary Progressive Aphasia

CILT + HD-tDCS as a Potential Treatment for Primary Progressive Aphasia
Recruiting
45 years - 80 years
All
Phase 2
62 participants needed
1 Location

Brief description of study

Primary Progressive Aphasia, or PPA, is a neurodegenerative disease that affects language abilities. A person with PPA may have difficulties speaking, understanding speech, reading, or writing, and these difficulties worsen over time.The purpose of this study is to determine whether a form of non-invasive brain stimulation called High-definition Transcranial Direct Current Stimulation (or HD-tDCS) can be used as a therapeutic technique, in combination with Constraint-Induced Language Therapy (CILT) to improve the language symptoms of PPA.

HD-tDCS uses a mild electrical current, about the same strength as a 9-volt battery, to stimulate regions of the brain from outside the head. This is performed using small electrodes placed on the scalp using an elastic band that help conduct the electrical signal into the brain. TDCS changes how responsive certain regions of the brain can be (i.e., more or less responsive). CILT is a form of speech therapy that focuses on improving speech production.

This study will use HD-tDCS combined with CILT to try to increase how responsive the language areas of the brain can be, in order to determine whether this type of stimulation can help enhance the benefits of CILT.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Primary Progressive Aphasia,Aphasia
  • Age: 45 years - 80 years
  • Gender: All

  • Ages 45-80 years old
  • Must have aphasia due to PPA
  • Native English Speaker

Updated on 04 Aug 2024. Study ID: 843286

Find a site

We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Email

View email

Phone

Phone country flag

View phone
Investigator Avatar

Primary Contact

First name*
Last name*
Email*
Phone number*
Preferred way of contact
Race
Ethnicity
Other language

Interested in the study

Select a study center that’s convenient for you, and get in touch with the study team.

Contact a study center