Transseptal vs. Retrograde Aortic Ventricular Entry to Reduce Systemic Emboli Multi-center comparative effectiveness randomized clinical trial to assess a transeptal approach to left ventricular ablation compared to a retrograd aortic aproach to prevent cerebral emboli and neurocognitive decline in adults with ventricular tacht=ycardia (VT) and /or premature ventricular contractions (PVCs)

Both transseptal and retrograde aortic approaches are routinely utilized in pediatric and adult cardiac electrophysiology and cardiac catheterization laboratories in the United States and have been in clinical practice for decades to treat multiple types of left atrial and ventricular arrhythmias. As either approach can be used to perform catheter ablation of ventricular tachycardia (VT) and premature ventricular contractions (PVCs), the decision is currently based on physician preference driven primarily by anecdote and personal experience.

You may be eligible for this study if you meet the following criteria:

• Conditions: Medical Research
• Age: 99 years or below
• Gender: All