UPCC 06717 / AMC 101: A Pilot Study | Clinical Research Studies Listing

Build status - In Progress

UPCC 06717 / AMC 101: A Pilot Study of Ibrutinib and R-da-EPOCH for Front Line Treatment of AIDS-Related Lymphomas

Recruiting

18 years - 64 years

All

Phase 1

5 participants needed

1 Location

Brief description of study

Non-Hodgkin lymphoma is a potentially curable condition with standard cancer treatment drugs (chemotherapy) and steroids. Standard lymphoma treatment includes chemotherapy, or cancer-fighting drugs, called etoposide, vincristine, cyclophosphamide, prednisone and doxorubicin (called EPOCH).

Detailed description of study

The main purpose of this study is to test the safety of an oral drug, ibrutinib, added to the standard lymphoma treatment.

We will also study whether ibrutinib has a helpful effect against HIV and other viruses in our bodies that can cause lymphoma.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

Conditions: Non-Hodgkin lymphoma,Diffuse Large B-cell Lymphoma,HIV+,
Age: 18 years - 64 years
Gender: All

Participants must have documented CD20 positive or negative diffuse large B-cell lymphoma (DLBCL).
Stage II-IV disease.
Documentation of HIV diagnosis.
Be 18–64 yrs of age.

Updated on 04 Aug 2024. Study ID: 828995

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